#$%^&*AU2013202114B220150326.pdf#####The present application relates to a composition comprising pantothenic acid (vitamin B5), or a pharmaceutically acceptable derivative, salt or prodrug thereof； folic acid (vitamin B9)； nicotinamide； a source of copper； and a source of zinc. The composition may further include biotin, vitamin A, silicon and/or Vitex angus-castus. The composition can be used in a method for reducing, treating and/or preventing acne and/or related skin disorders. Additionally, the composition can be used in a method for reducing, treating and/or preventing the appearance of acne and/or related skin disorders on the skin.
