The microbial scrub brush (20) employs an insert of foam material (22, 22, 22", 22", 47, 47) that is impregnated with an anti-bacterial disinfectant that is housed within a housing (21, 21, 51) of alcohol compatible material and sealed over by a removable lid (23). The insert (22, 22, 22", 22", 47, 47) is maintained in sterile condition until ready for use. After the removal of the lid (23), the insert of foam material (22, 22, 22", 22", 47, 47) is moved over the end of a female luer (40) and rotated in order to clean the outer surface of the luer (40) as well as the interior of the luer (40).
