Combination of histone deacetylase inhibitor and either Her2 inhibitor or PI3K inhibitor

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专利权人:

アセチロン ファーマシューティカルズ インコーポレイテッド

发明人:

ディヴィット・リー・タマング,ミン・ヤン,サイモン・エス・ジョーンズ

申请号：

JP2016521347

公开号：

JP6626437B2

申请日:

2014.10.06

申请国别(地区):

JP

年份:

2019

代理人:

摘要：

The invention relates to combinations comprising an HDAC inhibitor and a Her2 inhibitor for the treatment of breast cancer in a subject in need thereof. The invention also relates to combinations comprising an HDAC inhibitor and a PI3K inhibitor for the treatment of breast cancer in a subject in need thereof. Also provided herein are methods for treating breast cancer in a subject in need thereof comprising administering to the subject an effective amount of one of the above combinations. Further provided are methods for inhibiting migration and/or invasion of a breast cancer cell in a subject by administering to the subject a HDAC6 specific inhibitor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/