Hongmei Li;Zhaoning Zhu;Mark D. McBriar;Anandan Palani;Ruo Xu;Xianhai Huang;Gioconda Gallo;Zhiqiang Zhao;William J. Greenlee;Johannes;Theodros Asberom;Dmitri A. Pissarnitski;Xiaohong Zhu;Zhong-Yue Sun
发明人:
Zhaoning Zhu,William J. Greenlee,Zhong-Yue Sun,Gioconda Gallo,Theodros Asberom,Xianhai Huang,Xiaohong Zhu,Mark D. McBriar,Dmitri A. Pissarnitski,Zhiqiang Zhao,Ruo Xu,Hongmei Li,Anandan Palani,Johannes
申请号：
US12598704
公开号：
US08357682B2
申请日:
2008.05.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides a novel class of heterocyclic compounds of Formula (I) as modulators of gamma secretase, wherein the definitions of the variables of Formula (I) are defined herein, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
