Zhaoning Zhu,William J. Greenlee,Hongmei Li,Monica L. Vicarel,Jun Qin,Pawan Kumar Dhondi,Xianhai Huang,Anandan Palani,Xiaoxiang Liu,Zhong-Yue Sun,Hubert B. Josien,Ruo Xu,David James Cole,Duane A. Burn
申请号:
US13128316
公开号:
US08809318B2
申请日:
2009.11.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compostions.