A therapeutic shoe includes a main body, a sole located at one side of the main body, a vibration layer, and a power generating module. The vibration layer is located between the main body and the sole. The power generating module includes a power generating unit, a rectifying circuit and a vibration device, which are electrically connected in series. The power generating unit generates and induces induced current. The rectifying circuit receives, rectifies, amplifies and processes the induced current from the power generating unit. The vibration device is located at the vibration layer and receives the processed induced current from the rectifying circuit to vibrate according to a predetermined vibration frequency in the vibration layer.