A non-invasive urine collection device is disclosed that can be used by both male persons and female persons. For example, the urine collection device is designed such that through orientation and/or deformation, the urine collection device may be configured to seal around the human pelvic area to sanitarily and non-invasively collect urine. The collection device comprises a funnel with a drain as a first end and a receptacle opening at a second end opposite the first end, a handle on one side, and a flexible ring seal along the perimeter of the receptacle opening. The flexible ring seal, shape of the receptacle opening, and the angle of the funnel wall in relation to the receptacle opening and funnel drain is such that the collection device can be used in either a handle up or handle down orientation.
