To provide a technique to inhibit crystal deposition of a halogenated isoquinoline derivative-containing aqueous composition during low temperature storage.SOLUTION: The present invention provides a method for promoting migration of a compound represented by the following general formula (1) or a salt thereof or their solvates to eye tissue, including the step of causing methyl cellulose to be contained in an aqueous composition containing the compound represented by the following general formula (1) or a salt thereof or their solvates [where X is a halogen atom].SELECTED DRAWING: None【課題】ハロゲン化イソキノリン誘導体含有水性組成物の、低温保存時の結晶析出を抑制する技術の提供。【解決手段】次の一般式（１）［式中、Ｘはハロゲン原子を示す。］で表される化合物若しくはその塩又はそれらの溶媒和物を含有する水性組成物に、メチルセルロースを含有せしめる工程を含む、前記一般式（１）で表される化合物若しくはその塩又はそれらの溶媒和物の眼組織への移行の促進方法。【選択図】なし
