Engineered cells for inducing tolerance

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专利权人:

BioNTech SE;University of Verona

发明人:

Sahin, Ugur,Bronte, Vincenzo,Ugel, Stefano,Fiore, Alessandra

申请号：

AU2018209163

公开号：

AU2018209163A1

申请日:

2018.01.17

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The present invention relates to cells which are engineered so as to increase the cellular level of cellular FLICE [Fas-associated death domain (FADD)-like IL- 1 β-con verting enzyme] - inhibitory protein (CFLAR). The engineered cells have the ability to induce tolerance. Enhanced tolerogenicity is useful for prolonging survival of a foreign transplant and for treatment of autoimmune diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/