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Antibody against enzyme specifically cleaving von villebrand factor and assay system using the same
专利权人:
Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
发明人:
Nozaki, Chikateru,Maeda, Hiroaki,Hamamoto, Takayoshi,Mimura, Noriko,Soejima, Kenji,Nakagaki, Tomohiro
申请号:
AU2012203101
公开号:
AU2012203101B2
申请日:
2012.05.25
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2012203101B220141002.pdf#####ABSTRACT It is intended to provide an antibody showing immunoreactivity selectively to ADAMTS-13 and applications of this antibody in epitope analysis or diagnosis of an ADAMTS-13 autoantibody-positive patient. Alternatively, it is intended to provide a process for producing and use of a modified ADAMTS-13 molecule partially deleted aiming at the application in pharmaceutical products. An antibody specific for ADAMTS-13 which can be obtained from a warm-blooded animal immunized and sensitized with a polypeptide containing a part or the whole of ADAMTS-13 amino acid sequence; a process for producing an antibody comprising a step of immunizing and sensitizing a warm-blooded animal with a polypeptide containing a part or the whole of ADAMTS-13 amino acid sequence; use of the above-described antibody including a method of detecting and purifying ADAMTS-13; and a modified ADAMTS-13 molecule partially deleted are provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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