A patch preparation having a backing layer and a drug layerlaminated on the backing layer; wherein the drug layer contains anadhesive containing at least one compound selected from the groupconsisting of fentanyl and pharmaceutically acceptable salts thereof,polyisobutylene, and a silicon-containing polymer; and a mass ratio ofthe polyisobutylene and the silicon-containing polymer in the adhesiveis 20:1 to 7:3.