USE OF EXOPOLYSACCHARIDES FROM BACILLUS AMYLOQUENFACIENS IN MANUFACTURING COMPOSITIONS WITH HYPOGLYCEMIC EFFECT AND COMPOSISTIONS FOR AMELIORATING DIABETES AND COMPLICATIONS THEREOF
The present invention relates to a use of exopolysaccharides fromBacillus amyloquenfaciensin manufacturing compositions with hypoglycemic effect and compositions for ameliorating diabetes and complications thereof. The exopolysaccharides is extracted fromBacillus amyloquenfaciens, which isdeposited at Food Industry Research and Development Institute with an deposition No. BCRC 910697. The exopolysaccharides fromBacillus amyloquenfaciensin the present invention can increase the glucose uptake and is not affected by insulin resistance. Thus, it can replace insulin to treat insulin-dependent type 1 diabetic mellitus and non-insulin dependent diabetic mellitus.本發明提供了一種液化澱粉芽孢桿菌之胞外多醣用於製備改善糖尿病或其併發症藥物之用途。本發明另外又提供了一種液化澱粉芽孢桿菌之胞外多醣用於製備降血糖藥物之用途。所使用的液化澱粉芽孢桿菌寄存於食品工業發展研究所,編號為BCRC 910697。本發明液化澱粉芽孢桿菌之胞外多醣,可以促進細胞吸收代謝葡萄糖,取代胰島素刺激細胞,卻不受胰島素抗性的限制,則對於缺乏胰島素的第一型糖尿病患者,以及有胰島素抗性的第二型糖尿病患者,都可以應用。
