A needle-like body filled with a freeze-dried chemical solution is provided. A needle-like member (10) having a needle-like portion (102) on one side of a substrate and having a hollow hole (103) in the needle-like portion is prepared. Then, after the water-repellent treatment is applied to the tip portion of the needle-shaped portion (102), the needle-like member (10) and the chemical liquid are placed under reduced pressure to form a hollow hole (103) of the needle-(103) is brought into contact with the surface and brought into contact with the liquid surface of the chemical liquid and brought into contact with the hollow hole (103) of the needle-shaped body (10) to set the atmospheric pressure (first pressure), whereby the hollow hole . Thereafter, the drug solution filled in the hollow hole (103) is freeze-dried.内部に凍結乾燥された薬液が充填された針状体を提供する。基板の一方の面に針状部(102)を備え、該針状部に中空孔(103)を備える針状体(10)を用意する。そして、針状部(102)の先端部に撥水処理した後、針状体(10)及び薬液を減圧下に配置して、針状体(10)の中空孔(103)と薬液の液面を接触させ、針状体(10)の中空孔(103)と薬液の液面を接触させた状態で大気圧(第1の圧力)とすることで、中空孔(103)に薬液を充填する。その後、中空孔(103)に充填された薬液を凍結乾燥する。
