ДУЕВА-КОГАНОВ Ольга В. (US),КОРОСКЕНИЙ Балинт (US),ЧЖОУ Сяньчжи (US)
申请号：
RU2010147447/15
公开号：
RU2010147447A
申请日:
2009.04.15
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A cosmetically acceptable delivery system for a hydrophobic beneficial agent in a keratinized substrate, where the delivery system contains! i.) amphiphilic block copolymer,! moreover, the amphiphilic block copolymer includes a hydrophilic (A) block and a hydrophobic (B) block,! where the hydrophilic block (A) contains at least a cationic monomer unit or a potentially cationic monomer unit under conditions of use, and the unit is represented by the formula (I) or (II)! ! where R1 represents hydrogen or methyl,! R2 is hydrogen, branched or unbranched C1-4 alkyl,! R3 and / or R4 independently are branched or unbranched C1-22 alkyl, C1-C4 alkyl hydroxy, benzyl! or ! R3 and R4 can be combined to form a five- or six-membered ring with nitrogen, said ring containing one or more heteroatoms,! Z- is a conjugated acid base! X represents oxygen or -NR5,! moreover, R5 takes on values as indicated for R1 above,! A represents an alkylene group of 1-4 carbon atoms,! R6 and R7 are hydrogen, branched or unbranched C1-22 alkyl, benzyl or C1-C4 alkylhydroxy,! n and m are 2, 3, 4 or more； ! and! hydrophobic polymer block (B) contains siloxane monomer units! and! ii.) hydrophobic beneficial agent. ! 2. The delivery system according to claim 1, in which the hydrophobic block (B) contains siloxane monomer units of the formula (III)! ! R8 and R9 independently are C1-4 alkyl, phenylalkyl, alkoxy, aryl, aryloxy, alkylaryl, alkylamine, alkyl hydroxy, polyoxyalkylene, polyalkylene polyamine or! ! moreover, the polycationic block is defined1. Косметически приемлемая система доставки для гидрофобного полезного агента в ороговевший субстрат, где система доставки содержит ! i.) амфифильный блок-сополимер, ! причем амфифильный блок-сополимер включает гидрофильный (А) блок и гидрофобный (В) блок, ! где гидрофильный блок (А) содержит по меньшей мере катионное мономерное звено или потенциально катионное мономерное звено в условиях использования, и звено представлено формулой (I) или (II) !
