THE TEXAS A&M UNIVERSITY SYSTEM;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
发明人:
BIELKE, LISA,LAYTON, SHERRYLL,HARGIS, BILLY,PUMFORD, NEIL R.,FAULKNER, OLIVIA B.,BERGHMAN, LUC,ABI-GHANEM, DAAD
申请号：
CA2906079
公开号：
CA2906079A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD 154 polypeptide or an HMGB1 polypeptide.
