ARNINC GADLOR 1 ET 2 DANS LE TRAITEMENT ET LA PREVENTION DU REMODELAGE CARDIAQUE

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专利权人:

MEDIZINISCHE HOCHSCHULE HANNOVER

发明人:

HEINEKE, JORG,FROESE, NATALI

申请号：

CA3062724

公开号：

CA3062724A1

申请日:

2018.05.30

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention relates to a compound inhibiting the expression and/orthe activity of a long non-coding RNA(IncRNA) selected from GADLOR 1 and GADLOR 2 for use in treating or preventingcardiac remodelling, wherein GADLOR 1comprises or consists of a nucleic acid sequence selected from the groupconsisting of SEQ ID NOs 1 to 3 and sequences being at least75% identical thereto, and GADLOR 2 comprises or consists of a nucleic acidsequence selected from the group consisting of SEQ IDNOs 4 to 6 and sequences being at least 75% identical thereto.

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