The present invention discloses a saliva collection device provided with a collection tank for containing a liquid and a guide needle for guiding the liquid in the collection tank out of the collection tank, and a vacuum tube, wherein the vacuum tube is used to suck the liquid in the collection tank through the guide needle. The saliva collection device can accurately collect the saliva of a patient who can easily control the position of spitting saliva and the saliva volume, and can avoid collecting the foams in the saliva, so that the volume of the sampled saliva is more accurate.
