Process for the preparation of a chiral compound

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专利权人:

Thorsten Wilhelm

发明人:

Thorsten Wilhelm,Martin Langner

申请号：

US14125341

公开号：

US09493428B2

申请日:

2012.06.14

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention relates to a process for the preparation of a compound of formula (V), in particular posaconazole, wherein said process comprises the steps of (1) providing a mixture comprising a compound of formula (IV), a protic solvent system, and a suitable base and (2) heating the mixture of (1) to obtain a mixture comprising the compound of formula (V).

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