597704 Disclosed herein is the use of a cannabinoids, such as cannabidiol (CBD), in the treatment of epilepsy. Additionally disclosed is the use of a combination of cannabinoids, for example CBD and tetrahydrocannabivarin (THCV) in the treatment of epilepsy. The THCV may be used as a pure or isolated compound, or as a plant extract in which significant amounts of any THC naturally present has been selectively removed.