THIS INVENTION RELATES TO THE USE OF ONE OR MORE CANNABINOIDS IN THE TREATMENT OF EPILEPSY AND MORE PARTICULARLY TO THE USE OF ONE OR A COMBINATION OF CANNABINOIDS IN THE TREATMENT OF GENERALIZED OR PARTIAL SEIZURE. IN ONE EMBODIMENT IT RELATES TO THE USE OF THE CANNABINOID THCV, AS A PURE OR ISOLATED COMPOUND, OR AS A PLANT EXTRACT IN WHICH SIGNIFICANT AMOUNTS OF ANY THC NATURALLY PRESENT HAS BEEN SELECTIVELY REMOVED. IN ANOTHER EMBODIMENT THE PHYTOCANNABINOID IS CBD.