Recombinant dengue virus antigens comprising the C15 signal peptide, full-length PRM protein, and full-length E protein

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专利权人:

Doris Apt;Juha Punnonen;Alice M. Brinkman

发明人:

Doris Apt,Juha Punnonen,Alice M. Brinkman

申请号：

US12075097

公开号：

US08158131B2

申请日:

2008.03.07

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.

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