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NUEVOS DERIVADOS DE CICLOHEXILAMINA QUE TIENEN ACTIVIDAD COMO AGONISTAS ADRENERGICOS �2 Y COMO ANTAGONISTAS MUSCARINICOS M3
- 专利权人:
- ALMIRALL; S.A.
- 发明人:
- AIGUADE BOSCH, JOSE,GUAL ROIG, SILVIA,PRAT QUINONES, MARIA,PUIG DURAN, CARLOS
- 申请号：
- PE0005152014
- 公开号：
- PE12322014A1
- 申请日:
- 2012.11.09
- 申请国别(地区):
- PE
- 年份:
- 2014
- 代理人:
- 摘要：
- Refers to compounds such as Hydroxy Derivatives of cyclohexylamine (di - (2-thienyl) acetate trans-4 - [{{(3 - [6 - [(2R) - 2 - hydroxy - 2 - 8 - hydroxy - 2 - oxo - 1.2 - dihidroquinolin - 5 - il) ethyl] amine methyl}) - 2 - oxo - 1.3 - benzoxazole - 3 (2H) - il}] propyl Cyclohexyl (methyl) amino] -, dihidrofluoruro Hydroxy (di - (2-thienyl) Trans - 4 - [3 - [5 - ({{[(2R) - 2 - hydroxy - 2 - 8 - hydroxy - 2 - oxo - 1Dihidroquinolin - 2 - 5 - il) ethyl] amino] methyl) - 1H 1,2,3-benzotriazole - triazin-1-yl] propyl Cyclohexyl (methyl) amino]}, dihidrofluoruro Hydroxy (di - (2-thienyl) Trans - 4 - [3 - [5 - ({{[(2R) - 2 - hydroxy - 2 - 8 - hydroxy - 2 - oxo - 1.2 - dihidroquinolin - 5 - il) ethyl] amino] methyl) - 1H indole - triazin-1-yl] propyl Cyclohexyl (methyl) amino]}, dihidrof Luoruro Hydroxy (di - (2-thienyl) Trans - 4 - [3 - [5 - ({{[(2R) - 2 - hydroxy - 2 - 8 - hydroxy - 2 - oxo - 1Dihidroquinolin - 2 - 5 - il) ethyl] amino] methyl) - 1H benzimidazole - triazin-1-yl] propyl Cyclohexyl (methyl) amino]} among others. It also relates to a Pharmaceutical composition. These compounds are \ufffd2 adrenergic agonists and antagonists of Muscarinic m3 being useful in the treatment of pulmonary disease, glaucoma, asthmaSE REFIERE A COMPUESTOS DERIVADOS DE CICLOHEXILAMINA TALES COMO: HIDROXI(DI-2-TIENIL)ACETATO DE TRANS-4-[{3-[6-({[(2R)-2-HIDROXI-2-(8-HIDROXI-2-OXO-1,2-DIHIDROQUINOLIN-5-IL)ETIL]AMINO}METIL)-2-OXO-1,3-BENZOXAZOL-3(2H)-IL]PROPIL}(METIL)AMINO]-CICLOHEXILO, DIHIDROFLUORURO HIDROXI(DI-2-TIENIL)ACETATO DE TRANS-4-[{3-[5-({[(2R)-2-HIDROXI-2-(8-HIDROXI-2-OXO-1,2-DIHIDROQUINOLIN-5-IL)ETIL]AMINO}METIL)-1H-1,2,3-BENZOTRIAZOL-1-IL]PROPIL}(METIL)AMINO]CICLOHEXILO, DIHIDROFLUORURO HIDROXI(DI-2-TIENIL)ACETATO DE TRANS-4-[{3-[5-({[(2R)-2-HIDROXI-2-(8-HIDROXI-2-OXO-1,2-DIHIDROQUINOLIN-5-IL)ETIL]AMINO}METIL)-1H-INDOL-1-IL]PROPIL}(METIL)AMINO]CICLOHEXILO, DIHIDROFLUORURO HIDROXI(DI-2-TIENIL)ACETATO DE TRANS-4-[{3-[5-({[(2R)-2-HIDROXI-2-(8-HIDROXI-2-OXO-1,2-DIHIDROQUINOL
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
