ZAWEL,LEIGH,STRAUB CHRISTOPHER S.,FIRESTONE BRANT G.,DRANOFF GLEN,DOUGAN MICHAEL
申请号:
TN2010000512
公开号:
TN2010000512A1
申请日:
2010.11.05
申请国别(地区):
TN
年份:
2012
代理人:
摘要:
The present invention is directed to immune adjuvants containing IAP inhibitors, including Smac mimetics. The invention further provides pharmaceutical compositions and vaccines containing an IAP inhibitor and an antigen. Methods of enhancing an immune response by administration of an IAP inhibitor, methods of treating or preventing cancer, methods of treating or preventing infections, methods of treating autoimmune disorders, and methods of potentiating cytokine or antibody production are also provided.