University of the Witwatersrand, Johannesburg;Medical Research Council of South Africa
发明人:
申请号：
EP15157455.5
公开号：
EP2907519A1
申请日:
2006.10.13
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
An osteogenic device for use in a method of treating cancer in a mammal is provided. The osteogenic device comprises a carrier matrix, and an effective concentration of transforming growth factor beta 3 (TGF-β3) of at least 5µg per 100 mg of carrier matrix, the device being for implantation, preferably by injection directly into neoplastic primary and/or metastatic secondary masses, causing direct transformation of the neoplastic mass into bone thus facilitating its surgical debridement.
