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Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids
专利权人:
Zhen Huang
发明人:
Zhen Huang
申请号:
US13172559
公开号:
US08354524B2
申请日:
2011.06.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides selenium derivatives of nucleosides, nucleoside phosphoramidites, nucleotides, nucleotide triphosphates, oligonucleotides, polynucleotides, and larger nucleic acids and methods for their synthesis. Selenium derivatives of both ribonucleic acids and deoxyribonucleic acids, as well as methods for their synthesis, crystallization and uses in structural determinations, particularly by X-ray crystallographic techniques are disclosed. The selenium derivatives of the present invention are also useful as food supplements.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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