An object of the present invention is to provide a low molecular weight fucosylated glycosaminoglycan derivative (dLFG) exhibiting anticoagulant activity, a method for producing the same, a pharmaceutical composition containing the dLFG, a therapeutic agent for thrombosis, and the like. To achieve this object, the present invention provides a low molecular weight fucosylated glycosaminoglycan derivative exhibiting anticoagulant activity (derivative of Low molecular weight Glycosaminoglycan, dLFG), its production method, said dLFG or its production method And a use of the above-mentioned dLFG and the drug composition in the production of a thrombosis therapeutic agent. [Selection] Figure 10【課題】抗凝固活性を示す低分子量フコシル化グリコサミノグリカン誘導体(dLFG)、その製造方法、当該dLFGを含んでなる薬物組成物等及び血栓症治療薬等の提供を目的とする。【解決手段】この目的を達成するため、本発明は、抗凝固活性を示す低分子量フコシル化グリコサミノグリカン誘導体(derivateof Low molecular weight Fucosylated Glycosaminoglycan,dLFG)、その製造方法、前記dLFG又はその薬学的に許容可能な塩を含んでなる薬物組成物、及び前記dLFG及びその薬物組成物の血栓症治療薬の製造における用途等を提供する。【選択図】図10