Wherein R1 to R3 such as Please ask 1 of Entries to Ding the disease that Righteousness , Qi Fitness whats control Treatment characteristic As Fine Bao Over amounts proliferation or Iso is often proliferated to the compound of this Hair Ming Han Cover general formulas (1), the purposes that there is its Yong Yu System Prepare of Qie Han Cover aforementioned Xing Quality Medical Drug Group to close object.本發明涵蓋通式(1)之化合物其中R1至R3如請求項1所定義,其適於治療特徵為細胞過量增殖或異常增殖之疾病,且涵蓋其用於製備具有前述性質之醫藥組合物的用途。