DEFAUW, JEAN MARIE,HOLMSTROM, SCOTT DALE,CHEN, SHUHUI,ZHANG, YANG,WU, WENTAO,PENG, XIAN,MA, YUJUAN,LU, LUN
申请号：
MYPI 2013701314
公开号：
MY163262A
申请日:
2012.01.13
申请国别(地区):
MY
年份:
2017
代理人:
摘要：
PROVIDED ARE COMPOUNDS, AND SALTS THEREOF, OF FORMULA I: WHEREIN A IS R1 IS HYDROGEN, C1–C5 ALKYL, C1–C5 ALKOXY, C1–C5 HALOALKYL, C1–C5 ALKANOL, –(C1–C5 ALKYL)PHENYL, OR PHENYL, OR A GROUP OF THE FORMULA –C(O)-R12, WHERE R12 MAY BE C1–C5 ALKYL, C1–C5 ALKOXY, C1–C5 HALOALKYL, C1–C5 ALKANOL, –(C1–C5 ALKYL)PHENYL, OR PHENYL R2 AND R3 ARE INDEPENDENTLY HYDROGEN, C1–C5 ALKYL, C1–C5 ALKOXY, HALOGEN, C1–C5 HALOALKYL, OR C1–C5 HALOALKOXY R4 AND R5 ARE INDEPENDENTLY HYDROGEN, C1–C5 ALKYL, OR –(C1–C5 ALKYL)PHENYL R6 IS HYDROGEN, HYDROXY, OR IS ABSENT R7 IS HYDROGEN R8 AND R9 ARE INDEPENDENTLY HYDROGEN OR METHYL R10 IS HYDROGEN R11 IS HYDROGEN OR C1–C5 ALKYL OR R7 AND R10 COMBINE TO FORM –CH2- OR –(CH2)2- OR R8 AND R9 COMBINE TO FORM A CYCLOPROPYL GROUP WITH THE CARBON TO WHICH THEY ARE ATTACHED OR R10 AND R11 COMBINE TO FORM –CH2– OR –(CH2)3–. ADDITIONALLY, PHARMACEUTICAL FORMULATIONS AND METHODS OF USE EMPLOYING THE ABOVE COMPOUNDS ARE PROVIDED.
