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Acylguanidine derivatives
专利权人:
アステラス製薬株式会社
发明人:
木野山 功,宮本 聡,星井 博昭,宮▲ざき▼ 壮宏,山▲ざき▼ 真也子
申请号:
JP2008557144
公开号:
JP5287257B2
申请日:
2008.02.06
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
An object of the present invention is to provide a novel and excellent agent for treating or preventing dementia, schizophrenia and the like, based on the 5-HT 5A receptor modulating action. It was confirmed that a compound characterized by a structure that a tricyclic hetero ring having a pyrrole ring at the center and guanidine are bonded via a carbonyl group has a potent 5-HT 5A receptor modulating action and an excellent pharmacological action based thereon, and thus, it was found that the compound can be an excellent agent for treating or preventing dementia, schizophrenia, bipolar disorder, or attention deficit hyperactivity disorder, particularly for memory-related functional disorders such as cognitive impairments including dementia and schizophrenia, thereby completing the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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