NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE
- 专利权人:
- 发明人:
- KINOYAMA ISAO,MIYAZAKI TAKEHIRO,KOGANEMARU YOHEI,WASHIO TAKUYA,HAMAGUCHI WATARU
- 申请号:
- IN1162/CHENP/2012
- 公开号:
- IN2012CN01162A
- 申请日:
- 2012.02.06
- 申请国别(地区):
- IN
- 年份:
- 2012
- 代理人:
- 摘要:
[Object] An excellent agent for preventing or treating dementia, schizophrenia, and the like, based on serotonin 5-HT 5A receptor modulating action, is provided. [Means for Solution] It was confirmed that acylguanidine derivatives which have the characteristic structure in which the guanidine is bonded to one ring of the quinoline or isoquinoline via a carbonyl group, and a cyclic group is bonded to the other ring, exhibit potent 5-HT 5A receptor modulating actions and excellent pharmacological actions based on said 5-HT 5A receptor modulating action, and thus can be excellent agents for preventing or treating dementia, schizophrenia, bipolar disorder, or attention deficit hyperactivity disorder. Thus, the present invention has been completed.
[EP2463276A1]
- 来源网站:
- 中国工程科技知识中心