Low molecular weight heparins comprising at least one covalent bond with biotin or a biotin derivative, methods for their production and their use.

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专利权人:

サノフイ

发明人:

ユベール，フイリツプ,ムリエ，ピエール,ビスコブ，クリスチヤン,ユベール,フイリツプ,ムリエ,ピエール,ビスコブ,クリスチヤン

申请号：

JP2009549440

公开号：

JP5351770B2

申请日:

2008.02.12

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

Heparin derivatives (I) comprising a low molecular weight heparin chain covalently linked to biotin are new. Independent claims are also included for: (1) a process for preparing (I)； (2) use of avidin or streptavidin for neutralizing (I). ACTIVITY : Anticoagulant； Cerebroprotective； Neuroprotective. MECHANISM OF ACTION : Factor Xa inhibitor； Factor IIa inhibitor.

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中国工程科技知识中心

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http://www.ckcest.cn/home/