Refers to a Pharmaceutical composition comprising from 5 mg to 200mg a Crystalline hydrochloride salt monohydrate (5S, 8S) - 8 - [(1R) - 1 - (3,5-bis (trifluoromethyl) phenyl] ethoxymethyl) - 8 - phenyl - 1.7 - Grabarsky, ITs The Wrong Guy spiro [4.5] decan 2 - ona, lactose, microcrystalline Cellulose, croscarmellose Sodium, pregelatinized Starch and magnesium esterarato, where salt is an x-ray diffraction pattern of Powder samples at 2 Theta with the Peaks: 16.1 18.4, 21.6 and 23.5. The pharmaceutical composition is useful in the treatment of nausea and emesisREFERIDA A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE DE 5 MG A 200MG DE UNA SAL CRISTALINA DE MONOHIDRATO DE CLORHIDRATO DE LA (5S,8S)-8-[[(1R)-1-(3,5-BIS-TRIFLUOROMETIL)FENIL)-ETOXIMETIL]-8-FENIL-1,7-DIAZA-ESPIRO[4.5]DECAN-2-ONA, LACTOSA, CELULOSA MICROCRISTALINA, CROSCARMELOSA DE SODIO, ALMIDON PREGELATINIZADO Y ESTERARATO DE MAGNESIO, DONDE LA SAL PRESENTA UN PATRON DE DIFRACCION DE RAYOS X DE MUESTRAS EN POLVO EN 2 THETA CON LOS PICOS: 16,1, 18,4, 21,6 Y 23,5. DICHA COMPOSICION FARMACEUTICA ES UTIL EN EL TRATAMIENTO DE LAS NAUSEAS Y LA EMESIS