Christian KLEIN,Ekkehard MOESSNER,Diana DAROWSKI,Kay-Gunnar STUBENRAUCH
申请号：
US16576586
公开号：
US20200093861A1
申请日:
2019.09.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention generally relates to antigen binding receptors in new formats capable of specific binding to a tumor associated antigen. More precisely, the present invention relates to an antigen binding receptor which efficiently and specifically binds to/interacts with an antigen on the surface of a tumor cell, and to a T cell transfected/transduced with the antigen binding receptor. Furthermore, the invention relates to nucleic acid molecules and vectors encoding antigen binding receptors of the present invention. The invention also provides the production and use of T cells in a method for the treatment of particular diseases as well as pharmaceutical compositions/medicaments comprising antigen binding receptors and/or T cells of the present invention.
