Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd.
发明人:
Jijun Yuan,Xiangdong Qu,Jufang Lin,Xin Ye,Guoqing Cao,Weikang Tao,Lianshan Zhang,Lei Zhang,Li Yang
申请号:
US15103758
公开号:
US10344090B2
申请日:
2014.11.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides a human PD-1 antibody, an antigen-binding fragment thereof, and medical use thereof, and further provides a chimeric antibody and humanized antibodies comprising a complementarity-determining region (CDR) of the antibody, a pharmaceutical composition comprising the human PD-1 antibody and the antigen-binding fragment thereof, and use of the antibody in preparing medicines for treating diseases or disorders.