Jonnalagadda, Umamaheswararao;Forman, Stephen J.;Brown, Christine E.;Mardiros, Armen
发明人:
申请号：
EP14877876.4
公开号：
EP3094653B1
申请日:
2014.03.14
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Chimeric antigen receptors that include an antigen recognition domain； a spacer domain derived from a modified immunoglobulin Fc region having one or more mutations in its CH2 region resulting in impaired binding to an FcR； and an intracellular signaling domain.
