KASIA OWCZARCZYK,MICHAEL J. TOWNSEND,TIMOTHY W. BEHRENS
申请号:
BR112013021725
公开号:
BR112013021725A2
申请日:
2012.02.27
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Biological markers that predict patient responsiveness to B-cell antagonists are provided. Also provided are methods of using such biological markers. In addition, methods for identifying patients suffering from an autoimmune disease, e.g., rheumatoid arthritis, who are not likely to respond to B-cell antagonists are provided, as are methods of treating such patients. Methods for selecting therapeutic agents to treat such patients are also provided.