Timothy W. Behrens,Kasia Owczarczyk,Michael J. Townsend
申请号:
US15019615
公开号:
US09982302B2
申请日:
2016.02.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Biological markers that predict patient responsiveness to B-cell antagonists are provided. Also provided are methods of using such biological markers. In addition, methods for identifying patients suffering from an autoimmune disease, e.g., rheumatoid arthritis, who are not likely to respond to B-cell antagonists are provided, as are methods of treating such patients. Methods for selecting therapeutic agents to treat such patients are also provided.