Antibodies specific to folate receptor alpha (a.k.a.folate receptor 1 or FOLR1) and uses thereof for therapeutic and diagnostic purposes. Also provided herein are chimeric antigen receptors (CARs) comprising an extracellular antigen-binding fragment that binds FOLR1 and immune cells expressing such.葉酸受體阿法(亦即,葉酸受體1或FOLR1)特異性抗體及其在治療及診斷中之用途。本文還提供了嵌合抗原受體(chimeric antigen receptors,CARs),其包含與FOLR1結合的一胞外抗原結合片段以及表現該片段的免疫細胞。