Yan ling Yang,Chuan xiao Xue,Xi tian Zhang,Wei Xu,Yan Zhang
申请号：
US13264829
公开号：
US20120041035A1
申请日:
2010.06.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A levamlodipine compound pharmaceutical composition is provided, which contains levamlodipine or a pharmaceutically acceptable salt thereof, and chlorthalidone. In the present invention, levamlodipine and chlorthalidone are administrated in combination for treating hypertension, a high synergistic antihypertensive effect is achieved, and the edema side effect due to sodium and water retention caused when levamlodipine is administrated alone is mitigated. In addition, levamlodipine increases insulin sensitivity of an organism, and resists the side effect of increase in blood glucose level caused by chlorthalidone. The pharmaceutical composition of levamlodipine and chlorthalidone overcomes the disadvantage that levamlodipine takes effects slowly in hypertension repression.
