ILIN ALEXANDR IVANOVICH,KULMANOV MURAT ESENGALIEVICH
申请号：
IN4452/CHENP/2013
公开号：
IN2013CN04452A
申请日:
2013.06.11
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
in vivon3+ym+x y+x+kThe invention relates to the field of medicine and more specifically to an antibacterial agent for treating infectious diseases of bacterial origin including hospital acquired infections and drug resistant tuberculosis in the form of a nanostructured ionic complex synthesized from carbohydrates proteins and/or polypeptides (albumins interleukins interferons signal proteins etc.) which in order to enhance the antimicrobial effect through the activation of immunocompetent cells contain at least one terminal amino acid such as Phe Ala Val Ala Leu He etc. with electron donor functional groups iodine and alkaline and alkaline earth element halides in the fourth stage at a given ionic strength the antibacterial agent increases the sensitivity of bacteria including antibiotic resistant bacteria to antibiotics enhances monocyte and macrophage activity and increases the effectiveness of the antibiotic treatment of hospital acquired infections and drug resistant tuberculosis as well as having an antiviral effect stimulating the haematogenic function of the bone marrow and exhibiting an antitumour effect and radioprotective properties. With the components in acceptable concentrations the antibacterial agent can be used as a non medicinal agent (a biologically active additive or parapharmaceutical agent). The antibacterial agent is proposed in a pharmacological form that is suitable for parenteral oral external or other administration and the nanostructured ionic complex has the formula [{(L(MeI))[Me(L)I]}(Cl)] where ? = 30 300 kDa.
