TELLERS DAVID,COLLETTI STEVEN L,DUDKIN VADIM,IKEMOTO NORIHIRO,LIAO HONGBIAO,PARISH CRAIG,PEI TAO,SHAW ANTHONY,TRUONG QUANG,WANG LIJUN,YUAN YU,ZHU MAN
申请号:
HK15108687.4
公开号:
HK1208227A
申请日:
2015.09.07
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
Disclosed herein is a modular composition comprising 1) an oligonucleotide; 2) one or more tetraGalNAc ligands of Formula (I), which may be the same or different; optionally, 3) one or more linkers, which may be the same or different; and optionally, 4) one or more targeting ligands, solubilizing agents, pharmacokinetics enhancing agents, lipids, and/or masking agents.