A device and a method for controlling a temperature of a patient by an infusion of fluid. The device includes at least one supply of infusion fluid at least one body temperature input adapted to receive the actual body temperature of the patient and at least one additional input adapted to receive at least one additional parameter representing the actual physiological state of the patient. Furthermore, the device includes at least one control unit communicating with the body temperature input, and the additional input and at least one actuator, which is in fluid communication with the supply and which controls at least the actual flow rate and/or actual temperature of the infusion fluid in accordance with at least one control signal of the control unit. The method controls a temperature of a patient by an infusion of fluid using the device.