Duane D. Miller;Michelle D. Walker;Gabor Tigyi;Gangadhar G. Durgam;Tamas Virag;Ryoko Tsukahara
发明人:
Duane D. Miller,Gabor Tigyi,Gangadhar G. Durgam,Tamas Virag,Michelle D. Walker,Ryoko Tsukahara
申请号:
US13114010
公开号:
US20120135967A1
申请日:
2011.05.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are compounds according to formula (I) as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, treating a wound, treating apoptosis or preserving or restoring function in a cell, tissue, or organ, culturing cells, preserving organ or tissue function, and treating a dermatological condition.