RAMOT AT TEL-AVIV UNIVERSITY LTD.;EHUD GAZIT;RONIT SHALTIEL-KARYO
发明人:
EHUD GAZIT,RONIT SHALTIEL-KARYO
申请号:
IL21505411
公开号:
IL215054A
申请日:
2011.09.08
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
Isolated peptides are provided, being less than 20 amino acids in length. The peptides comprising an amino acid sequence GVLYVGSKTREGV (SEQ ID NO: 12) AAATGLVKREE (SEQ ID NO: 13) or GVVAAAEKTKQG (SEQ ID NO: 14), mimetics and/or fragment thereof, the peptides being capable of inhibiting alpha synuclein aggregation. Pharmaceutical compositions comprising same are also provided as well as uses thereof.