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LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
专利权人:
Bristol-Myers Squibb Company
发明人:
Donald J.P. Pinto,Mimi L. Quan,Michael J. Orwat,Yun-Long Li,Wei Han,Jennifer X. Qiao,Patrick Y.S. Lam,Stephanie L. Koch
申请号:
US15967149
公开号:
US20180244673A1
申请日:
2018.04.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present application describes lactam-containing compounds and derivatives thereof of Formula I:P4—P-M-M4  Ior pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
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