Donald J.P. Pinto,Mimi L. Quan,Michael J. Orwat,Yun-Long Li,Wei Han,Jennifer X. Qiao,Patrick Y.S. Lam,Stephanie L. Koch
申请号:
US16737261
公开号:
US20200140436A1
申请日:
2020.01.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present application describes lactam-containing compounds and derivatives thereof of Formula I:P4-P-M-M4 ; ; Ior pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.