"MODIFIED RELEASE PHARMACEUTICAL COMPOSITION AND A PROCESS FOR MANUFACTURING THE SAME".

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专利权人:

PANACEA BIOTEC LIMITED

发明人:

RAJESH JAIN,KOUR CHAND JINDAL,SANJAY BOLDHANE

申请号：

BRPI0807807

公开号：

BRPI0807807A2

申请日:

2008.01.24

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention refers to a modified release pharmaceutical composition comprising an in-situ gelling agent (=0.5 % w/w) and a gellation facilitating agent (e.g. calcium sulfate) in an amount of 2-17.5 % w/w. Additionally, the composition contains a release rate controlling polymer such as an acrylate and optionally a pH independent rate controlling polymer such as HPMC. A preferred active agent is mycophenolate mofetil. A process of making the above described composition is also disclosed.

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