An ultrasound applicator having spatially extended functionality to treat various oral and dental diseases. The applicator incorporates a multi directional ultrasound transducer system, which spatially irradiates the oral cavity with ultrasonic pressure waves, operational to simultaneously treat and destroy disease causing bacteria and bacterial chains on the gums and the inside surfaces of cheeks and lips, providing relief from Gingivitis, Recurring Aphthous Stomatitis, Lichen Planus, and Mucositis. A motorized version featuring sonic frequency orbital vibration of the applicator is described.