An instrument guide apparatus for use with a surgical or other guided intervention of a patient utilizing a guided instrument is disclosed. The instrument guide apparatus includes at least two line lasers mounted above the patient and generating intersecting planar laser lines along an instrument axis of entry in three-dimensional space above the patient. In an embodiment, the instrument axis of entry in three dimensional space above the patient is received from an imaging apparatus imaging the patients body at least along a portion of the instruments axis of entry into the patient. In an embodiment, the instrument axis of entry in three-dimensional space above the patient is a line-of-site for a camera mounted above the patient and controlled by the imaging apparatus.
