The Broad Institute Inc.;Massachusetts Institute of Technology
发明人:
Feng Zhang
申请号：
US14523799
公开号：
US09840713B2
申请日:
2014.10.24
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR/Cas system.
